|Sodium glucose co-transporter 2 (SGLT2) inhibitors are a relatively new class of drugs recommended for persons with type 2 diabetes who have poorly controlled blood glucose and high HbA1c levels.|
|Taken as an oral tablet.|
|There are three types of SGLT2 inhibitors that are currently available:|
|These pills work by preventing glucose from being absorbed in the kidneys. As a result, they decrease glucose in the blood and cause it to spill into the urine.|
|The treatment plan will differ for each person, but in general SGLT2 inhibitors are taken once a day before the first meal. The typical dose is 100 – 300 mg (canagliflozin), 5-10 mg (dapagliflozin), or 10 – 25 mg (empagliflozin), depending on the patient’s needs. In most cases, SGLT2 inhibitors are used in addition to other diabetes medications.|
WARNING! Women who are pregnant or who are breastfeeding should not take these medications. SGLT2 inhibitors are classified by the FDA as Category C drugs, which means that they are not considered safe during pregnancy.