|Alpha glucosidase inhibitors are recommended for persons with type 2 diabetes who have poorly controlled blood glucose despite using other diabetic medications. These are typically not first-line, but can be used in special situations. On average, most patients find that their Hb A1c levels drop by approximately 0.5% on these medications.|
Two types of alpha glucosidase inhibitors are available:
|These pills work in the patient’s gut by slowing the digestion and absorption of sugars from meals. This is accomplished by blocking an enzyme known as alpha glucosidase, which normally helps digest sugars in the small intestine.|
Acarbose and Miglitol are taken at the beginning of meals.
The treatment plan will differ for each patient, but in general:
• Acarbose is taken three times a day; the health care provider may gradually increase each dose from 25 mg to as much as 100 mg three times a day with meals.
• Miglitol is taken three times a day; the health care provider may gradually increase each dose from 25 mg to 50 mg three times a day with meals.